Neurological Development

Clinics


Center for Autism and Related Conditions

The UT Physicians Pediatric Center for Autism and Related Conditions recognizes that the challenges faced by children with developmental concerns are complex neurodevelopmental issues in which multiple developmental concerns likely overlap and require a comprehensive look at every child. This understanding guides our approach to utilizing patient-centered, evidence-based methods in our diagnostic evaluations and our treatment recommendations. We are a multi-disciplinary team that includes developmental and behavioral pediatrics, child psychology, and speech and language pathology.

Dan L Duncan Children's Neurodevelopmental Clinic

The Dan L Duncan Children's Neurodevelopment Clinic provides comprehensive assessments of children, adolescents, and young adults who are thought to have developmental or behavioral problems, autism spectrum disorders, attention-deficit/hyperactivity disorder (ADHD), and learning disabilities such as dyslexia.

Neuropsychological Services for Neurological Conditions Clinic

The Neuropsychological Services for Neurological Conditions Clinic evaluates both children and adults with a wide variety of illnesses affecting the central nervous system and cognitive function. Our clinical practice serves children age six and up, along with adults. Patients are referred from neurologists, neurosurgeons, and other medical practitioners in Houston and the surrounding area.


Programs


Act Early Texas!

Act Early Texas! is a set of online developmental and screening tools for parents who would like to learn more about their child’s development to determine if it is on schedule. Working in tandem with the Center for Disease Control, The Autism Center of The Children’s Learning Institute is directing state attention and efforts through Act Early Texas! to better address the needs of young Texas with autism spectrum disorders, identify the gaps in autism resources, and provide tools and resources for contacting pediatricians and other childhood specialists about potential developmental delays.

Brain, Behavior, and Injury Outcomes Program

This multidisciplinary program of research directed by Dr. Ewing-Cobbs includes longitudinal natural history studies as well as clinical trials examining a variety of outcomes in children and adults with acquired or developmental conditions that affect brain development and/or function.

Reach Out and Read

Reach Out and Read is a national program that prepares America’s youngest children to succeed in school by partnering with doctors to prescribe books and encourage families to read together. The Children's Learning Institute is home to the Texas branch of this program.

School-Based Tutoring Programs

Throughout the school year, our School-Based Programs provide early intervention to students who are at-risk for or who are experiencing reading and math failure as well as enrichment programs for students with grade level academic skills.

Summer Tutoring Programs

During the summer break, CLI Clinics provides hands-on tutoring in reading and math to help children prepare for the upcoming school year. These targeted tutoring programs can be instrumental in helping children develop the skills they need to be successful.

Treatment of Adult Severe TBI Using Autologous Bone Marrow Mononuclear Cells

This project will assess safety and functional outcomes following treatment of severe traumatic brain injury in adults using autologous bone marrow mononuclear cells.


Research


Autologous Cell Therapies for Cerebral Palsy

This clinical trial investigates autologous cell therapies in patients with cerebral palsy (CP). This study will compare the effects of two specific autologous cell therapies - bone marrow derived mononuclear cells (BMMNCs) versus human umbilical cord blood cells (HUCBs).

Brain-PALS MRI Study

The PALS-BRAIN MRI Study examines the role of parenting practices on brain development in toddlers. For this investigation structural and functional data are collected from children between the ages of 22 and 26 months. The goal of this investigation is to document the impact of an existing intervention on parenting practices on neurodevelopment during early childhood.

Developmental Consequences of Pediatric Traumatic Brain Injury

Information from this project will inform how we identify children who are not meeting developmental milestones and how we design developmentally appropriate supports for children after traumatic brain injury that will allow them to participate fully at home, in school, and in the community.

Lactoferrin for Prevention of Sepsis in Infants

The high frequency of serious infections in premature infants, as well as their associated morbidity and mortality, is a critical barrier to progress in improving infant care. Lactoferrin is a factor in milk that helps decrease infection and improves neurodevelopment due to its antimicrobial, anti-inflammatory, and immunomodulatory properties. This clinical trial will study the effect of lactoferrin on the occurrence of sepsis and to determine whether, as a result of decreased infections, infants grow and develop better after having been on lactoferrin.

Management of Myelomeningocele (MOMS2)

The major goals of this project are to acquire and quantitatively analyze MRI datasets collected as part of the MOMS2 follow-up study of children with spina bifida, who either had prenatal repair or postnatal repair of the myelomeningocele lesion.

Neural Correlates of Reading Comprehension in Typical and Struggling Readers: A Multimodal Neuroimaging Study

The major goals of this neuroimaging project are to evaluate school-aged children and their response to reading intervention as part of a multidisciplinary center on learning disabilities involving a consortium of three Texas universities (University of Houston, University of Texas at Austin, and UT Health).

Phase 2 Pediatric Autologous Bone Marrow Mononuclear Cells for Severe Traumatic Brain Injury

This purpose of this project is to determine the effect of intravenous infusion of autologous bone marrow mononuclear cells on brain structure and functional outcomes after severe traumatic brain injury in children. This study is designed as a prospective, randomized, placebo-controlled, blinded Phase 2 safety/biological activity study.

Traumatic Stress After Pediatric Injury: Neurobiological Influences

This study will examine the impact of traumatic injury on the biomarkers of three stress-responsive neurobiological systems and their relation to cognitive and psychological health outcomes during the first year after traumatic brain injury or extracranial injury.

Resources


Texas Infant, Toddler, and Three-Year-Old Early Learning Guidelines and Training

The purpose of the Texas Infant, Toddler, and Three-Year-Old Early Learning Guidelines is to outline expectations about what children should know and be able to do across domains of learning during specific age ranges and to outline steps for caregivers to support healthy development.

Texas Prekindergarten Guidelines and Training (2008)

The Texas Prekindergarten Guidelines, published in 2008, were developed to help educators provide all preschool children with the proper foundations for school success. CLI also created a web-based professional development tool to provide educators an introduction to the guidelines. This instrument includes video examples of child behaviors and classroom interactions and provides instructional strategies for teachers to support students.